As a sisterhood comprised primarily of Black, college-educated women, the Sorority seriously considers the issues impacting the Black community and boldly confronts the challenges of African Americans and, hence, all Americans. Over the years, a wide range of programs addressing education, health, international development, and the strengthening of African American families have evolved. The major programs of the Sorority are based upon the Five-Point Programmatic Thrust: economic development, educational development, international awareness and involvement, physical and mental health, and political awareness and involvement.

Since its founding in 1913 Delta Sigma Theta Sorority, Inc. has clearly distinguished itself as a public service organization that boldly confronts the challenges of African Americans and, hence, all Americans. Over the years, a wide range of programs addressing education, health, international development, and strengthening of the African American family have evolved. In realizing its mission, Delta Sigma Theta Sorority, Inc. provides an extensive array of public service initiatives through its Five-Point Programmatic Thrust